Science/Research thread by @Outdoctrination

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The NUMBER ONE food you need to eliminate to heal your gut.

SEED OILS - Why they are destroying your digestion:

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A large 6 month study showed that swapping out white rice and flour for soybean oil:

⬩INCREASED systemic inflammation
⬩DECREASED short chain fatty acids in the gut (vital for gut function/metabolism)
⬩INCREASED bacterial endotoxin synthesis

NOT a good sign...

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Seed oils given to animals mimics human inflammatory bowel disease progression

“The bottom line of our current study is that a soybean oil-enriched diet similar to the current American diet causes oxylipin levels to increase in the gut… which is consistent with IBD in humans.”

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“a diet high in soybean oil encourages the growth of adherent invasive E. coli in the gut… several beneficial bacteria in the gut are not able to withstand linoleic acid [main fat in seed oil] and die off. Adherent invasive E. coli has been identified in humans to cause IBD.”

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It is consistently and unequivocally shown that the amounts of omega 6 derived inflammatory compounds are in higher amounts, and directly drive digestive diseases, like IBS and IBDs

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One shocking analysis found that 30% of cases of inflammatory bowel disease were attributed to having any elevated intake of linoleic acid.

High linoleic acid intake DOUBLES the risk of ulcerative colitis, and the researchers stated that was probably an underestimate.

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Doctors will tend to stand by the old dogma that functional gut issues like IBS or indigestion are not inflammatory, but this is an insane viewpoint in light of the research.

These “normal” symptoms are simply the beginning of IBDs or even cancers. pic.x.com/4bq2bt82zn

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The fats most abundant in seed oils are precursors to several bioactive drivers of INFLAMMATION, which is ubiquitous in digestive issues.

These metabolites are the principal drivers of PAIN.

This process is especially important in the gut.

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Additionally, these fats are fragile and liable to chemical “spontaneous combustion,” damaging anything they’re in contact with and producing tons of toxins in the process.

These toxins can independently trigger further inflammation and pain directly through the nervous system.

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People with gut problems like IBS have higher levels of these omega 6 metabolites, and administering these metabolites directly causes pain and sensitivity in the bowel.

Seems pretty clear cut to me…

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If you’ve ever eaten a spicy hot chili pepper and it felt like your insides were being set on fire, you’ve experienced a glimpse into the high seed oil gut.

This pain and burning sensation is driven by TRPV1, whose endogenous activators are produced from the fats in these oils!

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People with gut problems tend to have more TRPV1 and more of these omega 6 TRPV1 activators.

This drives pain, sensitivity and discomfort during digestion.

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In fact, the amount of these omega 6 metabolites is directly related to how much bloating and gut pain people experience!

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People with IBS have elevations in all of the metabolites of these fats from seed oils.

Even the ones that aren’t classically considered inflammatory.

These fats ONLY come from the diet.

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It was first postulated decades ago that bowel diseases were really energy production problems.

Since then, this theory has been confirmed: mitochondrial metabolism in the gut is what shapes the bacterial composition, and in turn the health of digestion.

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Two of the best ways to poison your mitochondria are to

1. Have chronic inflammation, which reduces metabolism, and
2. Have lots of fragile fats in the mitochondria, which lowers energy production and is liable to destroy the mitochondria.

i.e, eat seed oils.

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People with IBS have secrete more:

- Prostaglandins, an inflammatory metabolite of omega 6 fats
- COX2 expression, the enzyme that synthesizes them

Mast cells that secrete these drive many of the symptoms of IBS, sensitizing pain and increasing the permeability of the gut.

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Histamine, also secreted by mast cells, is a key player in developing digestive issues, which we’ve covered here:

Dalton (Analyze & Optimize)@Outdoctrination

If you have chronic bloating and gut pain, this is for you.

This is A KEY culprit wreaking havoc on your gut that your doctor won’t even think about.

Here’s how it’s tearing up your insides (and what to do about it):

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Mast cells are activated by omega 6 fat metabolites!

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So besides not eating seed oils, what can you do to resolve this?

Vitamin E is the primary protector against the toxicity of these oils by:

- Preventing the “spontaneous combustion” of these fats, preventing damage
- Blocking the conversion to their inflammatory mediators

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Vitamin E has broad range protective effects on the gut

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In fact, 94% PERCENT of IBS patients are deficient in vitamin E.

Literally over 10 times as likely to be vitamin E deficient if you are struggling with gut issues.

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Administering vitamin E, by preventing inflammation, tissue damage and favorably changing the gut bacteria, prevents inflammatory bowel disease in animals.

Human equivalent dose of 3.35 mg / kg body weight, but this was injected so orally will likely be higher.

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To protect against the breakdown of seed oils, it’s around 2 mg vitamin E per gram PUFA

if you’re actively trying to reverse damage it’s probably quite a bit more.

Getting in all of the forms of vitamin E is KEY.

This is the best product I’m aware of.

healthnatura.com/whole-e-2oz/?r…

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Specifically getting all forms of vitamin E protects against intestinal inflammation

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The gut is the epicenter of most nagging symptoms

If you're looking for personalized help, our team of practitioners collaborate for those to help you your optimize gut and overall health.

Schedule a free consult here to see how we can help you! prism.miami/get-started

The NUMBER ONE food you need to eliminate to heal your gut. SEED...

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