If you've tried EVERYTHING and still can't lose weight, this is for...
Dalton (Analyze & Optimize)@Outdoctrination
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Jul 08, 2026
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If you've tried EVERYTHING and still can't lose weight, this is for you.
This is why your GUT is making you FAT (& what to do about it):
This is why your GUT is making you FAT (& what to do about it):
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20 years ago, it was discovered that:
1. Obese people have distinct gut bacteria vs lean people
2. Transferring the gut bacteria from an obese donor to a lean animal makes the animal fat
without changing diet.
The key is in the gut.
1. Obese people have distinct gut bacteria vs lean people
2. Transferring the gut bacteria from an obese donor to a lean animal makes the animal fat
without changing diet.
The key is in the gut.
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Shortly after, it was found that animals with NO gut bacteria DO NOT get fat, even with a junk food diet.
These animals had:
◇ Improved mitochondrial function (increased PGC1α, AMPK)
◇ Reduced flux of fat into fat tissue
making them resistant to getting fat.
These animals had:
◇ Improved mitochondrial function (increased PGC1α, AMPK)
◇ Reduced flux of fat into fat tissue
making them resistant to getting fat.
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Animals with no gut bacteria gain half the weight they "should" from what they eat.
Eliminating the bacteria allowed animals to stay lean despite eating the same amount of calories.
Eliminating the bacteria allowed animals to stay lean despite eating the same amount of calories.
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ENDOTOXIN (LPS) is the primary culprit here.
This is a part of most gut bacteria that has a ton of negative effects on the body.
⇨ Triggers inflammation systemically
⇨ Worsens mitochondrial function (energy production)
⇨ Increases serotonin
⇨ Prevents fat from "browning"
This means that your metabolism will be ruined with lots of endotoxin, and that can cause weight gain.
This is a part of most gut bacteria that has a ton of negative effects on the body.
⇨ Triggers inflammation systemically
⇨ Worsens mitochondrial function (energy production)
⇨ Increases serotonin
⇨ Prevents fat from "browning"
This means that your metabolism will be ruined with lots of endotoxin, and that can cause weight gain.
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Obese people have "bad bacteria" + more endotoxin.
Endotoxin comes from gut bacteria, but it becomes a problem systemically, since it is able to drive "leaky gut."
This means the gut becomes porous, and endotoxin can invade other parts of the body.
This destroys metabolism.
Endotoxin comes from gut bacteria, but it becomes a problem systemically, since it is able to drive "leaky gut."
This means the gut becomes porous, and endotoxin can invade other parts of the body.
This destroys metabolism.
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Endotoxin (from gut bacteria) causes obesity + insulin resistance, regardless of calories.
Administration of endotoxin:
◇ Increases fat gain
◇ Increases insulin
◇ Increases blood sugar
◇ Fattens the liver
basically causing diabetes all on its own.
Administration of endotoxin:
◇ Increases fat gain
◇ Increases insulin
◇ Increases blood sugar
◇ Fattens the liver
basically causing diabetes all on its own.
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Antibiotics prevent fat gain and insulin resistance, even when eating junk food.
Low dose, broad spectrum antibiotics:
◈ Reduced blood sugar
◈ Reduced insulin
◈ Reduced fat gain
despite eating MORE of a fattening diet.
Low dose, broad spectrum antibiotics:
◈ Reduced blood sugar
◈ Reduced insulin
◈ Reduced fat gain
despite eating MORE of a fattening diet.
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Antibiotics reverse leaky gut + inflammation.
Once again, low dose + broad spectrum antibiotics:
➔ Reduces intestinal permeability
➔ Reduces oxidative stress
➔ Lowers inflammation
from a junk food diet.
This is the power of reducing endotoxin.
Once again, low dose + broad spectrum antibiotics:
➔ Reduces intestinal permeability
➔ Reduces oxidative stress
➔ Lowers inflammation
from a junk food diet.
This is the power of reducing endotoxin.
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Gut inflammation makes you fat, by increasing serotonin.
Obese individuals have higher serotonin release from the gut than lean people.
Serotonin is released when there is endotoxin or other gut inflammation.
More on that below.
Obese individuals have higher serotonin release from the gut than lean people.
Serotonin is released when there is endotoxin or other gut inflammation.
More on that below.
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Lowering gut serotonin prevents fat gain, increases metabolism.
Serotonin released systemically lowers metabolism.
◇ Prevents "browning" of fat - which increases energy production
◇ Drives insulin resistance
◇ Fattens the liver
again, without increasing calories.
Serotonin released systemically lowers metabolism.
◇ Prevents "browning" of fat - which increases energy production
◇ Drives insulin resistance
◇ Fattens the liver
again, without increasing calories.
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Probiotics can prevent obesity, by reducing serotonin.
The bacteria B. Vulgatus was shown to:
◈ Reduce gut serotonin / inflammation
◈ Lower body fat
◈ Increase muscle mass
◈ Prevent liver fat
Treating the gut can absolutely help you achieve the body you want.
The bacteria B. Vulgatus was shown to:
◈ Reduce gut serotonin / inflammation
◈ Lower body fat
◈ Increase muscle mass
◈ Prevent liver fat
Treating the gut can absolutely help you achieve the body you want.
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Probiotics can prevent obesity.
L. Rhamnosus completely prevents fat gain from a junk food diet, without reducing calories.
It does this by reducing endotoxin containing bacteria,
and also by improving leptin resistance.
More on that below.
L. Rhamnosus completely prevents fat gain from a junk food diet, without reducing calories.
It does this by reducing endotoxin containing bacteria,
and also by improving leptin resistance.
More on that below.
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Butyrate increases metabolism, prevents fat gain.
Butyrate is a product & driver of a healthy gut.
It has multiple beneficial effects on mitochondrial function:
➔ Increases PGC1a (multiplies mitochondria)
➔ Ups UCP1 (more heat generation)
Giving it anti-obesity properties.
Butyrate is a product & driver of a healthy gut.
It has multiple beneficial effects on mitochondrial function:
➔ Increases PGC1a (multiplies mitochondria)
➔ Ups UCP1 (more heat generation)
Giving it anti-obesity properties.
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I've written about the benefits and role of butyrate in the gut here:
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Ultimately, you will want to take a comprehensive approach to healing the gut, especially if your goal is fat loss.
Below is my masterclass on doing just that:
Below is my masterclass on doing just that:
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Of course, all of this can be difficult to figure out on your own, but we are here for you.
If YOU want personalized help from us with your health, click where it says “schedule a free call” here: prism.miami
If YOU want personalized help from us with your health, click where it says “schedule a free call” here: prism.miami