Science/Research thread by @Outdoctrination

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One of the most potent cancer remedies on the planet is sitting in your cabinet, and cost you next to nothing.

It reduces the risk of getting and dying from literally every cancer you can think of.

It’s ASPIRIN, and you won’t believe the science behind it:

Dalton (Analyze & Optimize)@Outdoctrination

Modern medicine’s greatest contribution to the health of mankind.

It heals cancer, depression and is even a nootropic.

And it’s safe and cheap to boot.

Why ASPIRIN is so much more than a painkiller and a blood thinner:

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Aspirin reduces pancreatic tumor growth.

One of the most deadly in existence, with just 12% surviving past 5 years with it.

Aspirin:

◇ Reduces inflammation
◇ Reduces cancer stem cells
◇ Inhibits fibrosis

Giving it effectiveness on its own, & enhances chemo treatment.

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Aspirin reduces pancreatic cancer (& death) by ~60-70%.

Aspirin improves:

◇ Incidence
◇ Total survival
◇ Disease free survival
◇ Metastasis free survival

These effects were superior to even being a healthy weight, and NOT seen for other NSAIDs.

Baby aspirin (81 mg) use.

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Aspirin strikingly protective for breast cancer.

Breast cancer thrives on:

◈ Thromboxanes: inflammatory mediators inhibited with aspirin use
◈ Estrogen: which aspirin lowers

Reducing both breast cancer risk and metastasis experimentally.

Dalton (Analyze & Optimize)@Outdoctrination

Aspirin actually can counteract ESTROGEN as well.

Aspirin is an aromatase inhibitor, and can lower levels of estrogen.

Excess estrogen can give you love handles, that “tired but wired” type feeling, among other things.

Just 100 mg (little over a baby aspirin) daily.

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Aspirin shrinks deadly biliary cancers.

Another cancer with an extremely poor survival rate (10% after 5 years), cholangiocarcinoma kills 90% of people within 5 years.

Yet aspirin powerfully reduces its growth by influencing the production of signaling molecules called miRNAs.

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In fact, aspirin reduces the risk of getting biliary cancer by 3-4X.

85% reduction in risk for using baby aspirin for 3+ years.

This is absolutely insane, but we'll never hear about it because aspirin is no longer under patent and cheap - making it useless to pharma.

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Aspirin reduces liver cancer growth.

◇ Inhibits NF-κB - the master inflammatory regulator
◇ Promotes cancer cell suicide (ferroptosis)
◇ Inhibits HIF-1α - another cancer hallmark that diminishes mitochondrial metabolism.

Parallels the benefits of people taking baby aspirin.

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Aspirin shrinks skin tumors.

~325 mg (human equiv) aspirin daily:

☆ Lowers IL-3, NF-kB, PGE2
☆ Reduces tumor volume
☆ Prevents angiogenesis
☆ Halts metastasis

Again, corroborating the lower cancer risks of people taking aspirin regularly.

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Aspirin reduces ovarian tumor growth.

Here, it was shown to activate p53, a protein notoriously mutated in cancer.

p53 is literally known as a tumor suppressor gene - HALF of all cancers involve its malfunction.

Incredible.

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Aspirin + vitamin C is a powerful combination for cancer.

The combination seems to have a synergy, mainly by preventing excess oxidative stress and inflammation.

It's also highly selective - keeping normal cells healthy.

More on vitamin C below.

Dalton (Analyze & Optimize)@Outdoctrination

VITAMIN C:

⇨ Anti-cancer
⇨ Lowers stress
⇨ Renews skin
⇨ Improves sex life
⇨ Enhances energy & motivation
⇨ Crushes anxiety
⇨ Reduces sickness

& more.

Let's talk about the benefits of it, how to get enough and supplementation.

THREAD:

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A review of 118 studies showed that aspirin SUBSTANTIALLY reduces all cancer risk.

They also found minimal risks for bleeding.

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Aspirin reduces death from cancer, and from bleeding.

Another review of 51 human experiments confirmed reductions in all sorts of cancers.

They also found REDUCED fatal bleeds, the main risk associated with aspirin use.

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Aspirin works by a TON of different mechanisms to suppress cancer.

Of course, it reduces inflammation, which is a core characteristic of cancer.

But beyond that, it is able to modify the functioning of multiple proteins by acetylating them.

Some key ways it works:

◇ Suppresses glutamine metabolism
◇ Lowers HIF1α
◇ Suppresses Wnt signaling
◇ Increases mitochondrial metabolism, lowers glycolysis (decreases Warburg effect)
◇ Inhibits mTOR
◇ Increases AMPK
◇ Restricts angiogenesis

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It's no wonder one group called aspirin a "master regulator of the hallmarks of cancer."

It really is.

If you want to learn more about some of the hallmarks of cancer, check out the thread below.

Dalton (Analyze & Optimize)@Outdoctrination

Cancer is complicated.

Unfortunately, most treatments are very simple.

These are the 10 hallmarks of cancer,

and what I would do to address each one.

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The studies showing benefit in people are with it's consistent use at the baby dose (81 mg).

The risks have, in my view, been massively overblown, but are important to be aware of nonetheless.

Dalton (Analyze & Optimize)@Outdoctrination

The big concern is around the effects of aspirin on bleeding, especially in the gut.

As someone who has struggled with gut issues in the past and puts a ton of emphasis on gut health, I’m extremely cautious about anything involving the gut.

I believe that the narrative is a bit misconstrued.

First, the risk seems to be massively overblown. The risk of a placebo causing GI bleeding is around 5 in 1000, and it is 8 in 1000 for aspirin use. On top of this, aspirin actually seems to protect against the fatal, more serious type of gut bleeding.

Second, there are a few measures you can take to avoid this. Dissolving it in water helps avoid having it concentrated in one patch of your gut. Adding glycine (2:1 aspirin to glycine, sold as Glyprin) and baking soda (⅓ teaspoon) also completely protect against these issues.

Lastly, this seems to be transient, with the gastric mucosa adapting in just a few days to aspirin.

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This is the aspirin product we like to use, comes with a baby scooper and is pure and free of additives unlike the commercial brands. healthnatura.com/aspirin-powder…

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One of the most potent cancer remedies on the planet is sitting in...

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