@Outdoctrination: Your body’s ultimate neuroprot...
@Outdoctrination
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Mar 15, 2025
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Your body’s ultimate neuroprotective, mood enhancing, and mental health bolstering endogenous steroid: PREGNENOLONE
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Be sure to check out our video on the topic we recently released, which goes into greater detail about all of these topics. youtu.be/XC7iS11mI9I
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Pregnenolone increases energy production in mitochondria and supports their structure.
The brain, being the most energy-demanding organ, benefits greatly from this effect.
The brain, being the most energy-demanding organ, benefits greatly from this effect.
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This increased energy production supports myelination, which is the formation of a lipid coating called myelin around neurons.
Myelination is crucial for proper neuron function, as it helps facilitate proper firing and signal transduction.
Myelination is crucial for proper neuron function, as it helps facilitate proper firing and signal transduction.
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Microtubules are structural components that help maintain tissue integrity and allow cells to move efficiently.
In the brain, microtubules play a vital role in overall cell and tissue health.
Pregnenolone supports the formation and structure of microtubules.
In the brain, microtubules play a vital role in overall cell and tissue health.
Pregnenolone supports the formation and structure of microtubules.
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Neural stem cells are "baby cells," differentiating into various types of neurons.
Pregnenolone supports the growth these cells, aiding in the preservation brain tissue.
This is particularly important in cognitive decline, where structural breakdown of brain tissue occurs.
Pregnenolone supports the growth these cells, aiding in the preservation brain tissue.
This is particularly important in cognitive decline, where structural breakdown of brain tissue occurs.
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The famous BDNF acts through the receptor TRKB, where it plays a critical role in neuron development, growth and survival.
DHEA, a closely related metabolite of pregnenolone, has been shown to be the endogenous ligand for this receptor, and confers neuroprotection. @nootbro
DHEA, a closely related metabolite of pregnenolone, has been shown to be the endogenous ligand for this receptor, and confers neuroprotection. @nootbro
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Pregnenolone was thought to have beneficial effects on psychomotor skills like coordination as well as memory and learning in the 1940s.
The role of pregnenolone and its metabolites have since been more firmly established as critical to these processes.
The role of pregnenolone and its metabolites have since been more firmly established as critical to these processes.
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Allopregnanolone, a metabolite of pregnenolone, seems to be a pro-dopamine and anti-serotonin steroid.
This is incredibly important for reasons we've described here:
This is incredibly important for reasons we've described here:
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Quietly, pharma has been developing and bringing onto the market a patented, injectable form of allopregnanolone as a rapid acting antidepressant for postpartum depression.
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When administered pregnenolone, the amygdala, the brain's emotional center, exhibits reduced connectivity to higher cognitive regions.
This means that negative emotions have less influence on one's overall perspective and well-being, which was reported by the subjects.
This means that negative emotions have less influence on one's overall perspective and well-being, which was reported by the subjects.
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I can certainly attest to this finding.
Once I started using pregnenolone, that worry and chatter that would constantly crowd my thoughts quieted down.
I feel better about myself and my place in the world.
I feel less doubt.
In my head, I call it “the great stabilizer.”
Once I started using pregnenolone, that worry and chatter that would constantly crowd my thoughts quieted down.
I feel better about myself and my place in the world.
I feel less doubt.
In my head, I call it “the great stabilizer.”
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Human studies have demonstrated these effects, particularly in conditions like schizophrenia characterized by excess serotonin.
Pregnenolone also protects against glutamate excitotoxicity, another common characteristic of neurodegenerative diseases.
Pregnenolone also protects against glutamate excitotoxicity, another common characteristic of neurodegenerative diseases.
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Pregnenolone has also demonstrated some benefits in bipolar depression.
Its effects on emotional regulation and mood stabilization may contribute to its potential in managing this condition.
Its effects on emotional regulation and mood stabilization may contribute to its potential in managing this condition.
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By acting favorably on fundamental pathways that support energy production and lower stress, pregnenolone has a multitude of benefits to the structure and functioning of the brain.
This is the pregnenolone we use for these benefits: healthnatura.com/pregnenolone-2…
This is the pregnenolone we use for these benefits: healthnatura.com/pregnenolone-2…
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