Dr. Benjamin Bikman is a world-leading expert in insulin resistance...
Andrew Panella@Longevity_EDU
53 views
Jan 14, 2026
~3 min read
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Dr. Benjamin Bikman is a world-leading expert in insulin resistance and fat loss.
He just did a 2-hour podcast with Steven Bartlett.
It's hit about 1 Million views in 4 days.
Here are the top 10 lessons that go against everything mainstream health advice taught you 🧵
He just did a 2-hour podcast with Steven Bartlett.
It's hit about 1 Million views in 4 days.
Here are the top 10 lessons that go against everything mainstream health advice taught you 🧵
1:30
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1. Insulin is massively underrated.
It controls what every cell does with energy.
From your brain to your bones, insulin dictates whether you burn or store fat.
When insulin is high, your body is in storage mode.
It literally cannot burn fat.
It controls what every cell does with energy.
From your brain to your bones, insulin dictates whether you burn or store fat.
When insulin is high, your body is in storage mode.
It literally cannot burn fat.
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2. Calories matter less than you think.
Dr. Bikman explains that two meals with identical calories produce completely different results based on insulin response.
The low-carb meal increases metabolic rate.
The high-carb meal tanks it.
Same calories, opposite outcomes.
Dr. Bikman explains that two meals with identical calories produce completely different results based on insulin response.
The low-carb meal increases metabolic rate.
The high-carb meal tanks it.
Same calories, opposite outcomes.
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3. You CANNOT get fat without insulin.
Type 1 diabetics who stop taking insulin eat thousands of calories and lose weight rapidly.
Give them insulin and they gain fat eating less.
Studies prove this.
Remove insulin and fat storage becomes impossible.
Type 1 diabetics who stop taking insulin eat thousands of calories and lose weight rapidly.
Give them insulin and they gain fat eating less.
Studies prove this.
Remove insulin and fat storage becomes impossible.
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4. High insulin can lead to hunger.
When you spike insulin, it can:
- Drive glucose into storage
- Block ketone production in your liver
- Starve your brain of its two main fuels.
The result is ravenous hunger while you have massive fat stores your body cannot access.
When you spike insulin, it can:
- Drive glucose into storage
- Block ketone production in your liver
- Starve your brain of its two main fuels.
The result is ravenous hunger while you have massive fat stores your body cannot access.
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5. Ketosis supercharges fat burning.
Dr. Bikman's lab found that ketones increase metabolic rate in fat tissue by 3X
.
Even better, you literally waste calories by breathing and urinating out ketones.
Low insulin turns your body into a fat-burning machine.
Dr. Bikman's lab found that ketones increase metabolic rate in fat tissue by 3X
.
Even better, you literally waste calories by breathing and urinating out ketones.
Low insulin turns your body into a fat-burning machine.
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6. Liver fat drops 60% in one week.
When insulin falls on a ketogenic diet, the liver cannot store fat. It must burn it.
Human studies show that significant fatty liver disease can be slashed by 60% in just 7 days.
Same calories as a high-carb diet.
Opposite results.
When insulin falls on a ketogenic diet, the liver cannot store fat. It must burn it.
Human studies show that significant fatty liver disease can be slashed by 60% in just 7 days.
Same calories as a high-carb diet.
Opposite results.
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7. Hunger always wins against calorie cutting.
Every diet works until you stop doing it.
Too much calorie restriction means constant hunger and your willpower eventually fails.
Lower insulin first. Eat protein and fat freely.
They keep you full.
Every diet works until you stop doing it.
Too much calorie restriction means constant hunger and your willpower eventually fails.
Lower insulin first. Eat protein and fat freely.
They keep you full.
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8. Protein and fat are your allies.
They have little to no effect on insulin.
Anytime you're hungry, eat something with protein and fat.
You stay full longer, insulin stays low and your body keeps burning fat.
They have little to no effect on insulin.
Anytime you're hungry, eat something with protein and fat.
You stay full longer, insulin stays low and your body keeps burning fat.
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9. GLP-1 drugs like Ozempic work until they don't.
After 2 years, sweet cravings return to baseline.
70% of people quit the drug.
Even worse, 40% of weight lost can come from lean mass, not fat.
You still need healthy and sustainable lifestyle changes.
After 2 years, sweet cravings return to baseline.
70% of people quit the drug.
Even worse, 40% of weight lost can come from lean mass, not fat.
You still need healthy and sustainable lifestyle changes.
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10. Liposuction proves fat cell size matters.
You can surgically remove 20 lbs of pure fat and no health marker improves.
Diabetics stay just as diabetic.
Why?
Because health comes from shrinking fat cells, not removing them.
Lower insulin to shrink them naturally.
You can surgically remove 20 lbs of pure fat and no health marker improves.
Diabetics stay just as diabetic.
Why?
Because health comes from shrinking fat cells, not removing them.
Lower insulin to shrink them naturally.
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The Bottom Line:
The calorie-centric model of weight loss has failed millions of people for decades.
Insulin is the true controller of fat storage and most clinicians don't fully understand it.
Lower your insulin first.
Fat loss follows naturally.
The calorie-centric model of weight loss has failed millions of people for decades.
Insulin is the true controller of fat storage and most clinicians don't fully understand it.
Lower your insulin first.
Fat loss follows naturally.
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If you liked this thread:
1. Follow me here 👉@Longevity_EDU for more
2. Bookmark the tweet below to save this for later and retweet it to share this with others:
1. Follow me here 👉@Longevity_EDU for more
2. Bookmark the tweet below to save this for later and retweet it to share this with others:
Andrew Panella@Longevity_EDU
Dr. Benjamin Bikman is a world-leading expert in insulin resistance and fat loss.
He just did a 2-hour podcast with Steven Bartlett.
It's hit about 1 Million views in 4 days.
Here are the top 10 lessons that go against everything mainstream health advice taught you 🧵
He just did a 2-hour podcast with Steven Bartlett.
It's hit about 1 Million views in 4 days.
Here are the top 10 lessons that go against everything mainstream health advice taught you 🧵
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If you're a high achiever wanting to lose over 20lbs and reduce insulin resistance:
👉DM me "HEALTH"
We'll talk about how you can do it:
- With a healthy diet you enjoy
- Training 90 mins/week at home
- Without tracking calories or starving
x.com/messages/compo…
👉DM me "HEALTH"
We'll talk about how you can do it:
- With a healthy diet you enjoy
- Training 90 mins/week at home
- Without tracking calories or starving
x.com/messages/compo…
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Here are the results of a few of my clients.
If you want the same, DM me "HEALTH" through the button in the tweet above
If you want the same, DM me "HEALTH" through the button in the tweet above
2:18
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Credit to @BenBikmanPhD and @StevenBartlett for this podcast and these health lessons.
Here is the link to the full podcast. Check it out and subscribe!
youtu.be/C7LL7VwP8Nc?si…
Here is the link to the full podcast. Check it out and subscribe!
youtu.be/C7LL7VwP8Nc?si…
