@Outdoctrination: THIS might just be causing you...
@Outdoctrination
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Mar 15, 2025
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The FDA classifies most of these ingredients as “generally recognized as safe,” a nice way of saying they get put into the food based on expert opinion with minimal study.
While food additives have long played a role in enhancing flavor, prolonging shelf life, and improving texture, recent studies suggest they may be double agents with hidden agendas in our gut's ecosystem.
While food additives have long played a role in enhancing flavor, prolonging shelf life, and improving texture, recent studies suggest they may be double agents with hidden agendas in our gut's ecosystem.
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Specifically, Polysorbate 80 and carboxymethylcellulose seem to foster an environment ripe for mucus-degrading bacteria, degrading this layer of critical protection and paving the way for conditions like colitis and metabolic syndrome in animals.
Germ-free mice receiving fecal transplants from P80 and CMC-treated counterparts displayed similar microbial disruptions, demonstrating the cause and effect relationship.
Germ-free mice receiving fecal transplants from P80 and CMC-treated counterparts displayed similar microbial disruptions, demonstrating the cause and effect relationship.
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The detrimental effects extend beyond physical health.
P80 and CMC are implicated in altering behaviors.
Female mice, for instance, exhibited antisocial tendencies, while their male counterparts showed increased anxiety levels.
These behavioral changes align with identifiable shifts in the gut bacteria and levels of specific neuropeptides.
This should come as no surprise, the mental health connection to poor gut health is obvious and well understood at this point.
P80 and CMC are implicated in altering behaviors.
Female mice, for instance, exhibited antisocial tendencies, while their male counterparts showed increased anxiety levels.
These behavioral changes align with identifiable shifts in the gut bacteria and levels of specific neuropeptides.
This should come as no surprise, the mental health connection to poor gut health is obvious and well understood at this point.
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Artificial sweeteners also don't spare the gut.
These sweeteners, found in numerous diet foods and beverages, are linked to glucose intolerance and gut dysbiosis in animal models.
One study highlighted that prolonged saccharin intake led to glucose intolerance and changes in the fecal metabolites of mice, suggesting that these sweeteners might instigate metabolic disorders through inducing gut bacterial overgrowth.
These sweeteners, found in numerous diet foods and beverages, are linked to glucose intolerance and gut dysbiosis in animal models.
One study highlighted that prolonged saccharin intake led to glucose intolerance and changes in the fecal metabolites of mice, suggesting that these sweeteners might instigate metabolic disorders through inducing gut bacterial overgrowth.
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It’s also recently been shown that the ubiquitous food dye, red 40 or Allura Red AC, can cause inflammatory bowel disease outright, you guessed it, by increasing gut serotonin.
This was mediated by inducing dysbiosis and subsequent inflammation in the gut, along with increasing intestinal permeability.
This was mediated by inducing dysbiosis and subsequent inflammation in the gut, along with increasing intestinal permeability.
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You can read more about serotonin’s impact on your gut here:
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In regulatory circles, the FDA and EFSA have been basing food additive approvals on outdated safety testing from the 70s and 80s.
The increasing evidence of food additives’ negative impact on gut health cannot be ignored, with the FDA responding by calculating dietary exposure to emulsifiers and assessing their safety anew.
However, this FDA study has its limitations, looking retrospectively only up to 2010.
The quick pace at which the food industry and additive use are growing means regulations will likely never keep up.
The increasing evidence of food additives’ negative impact on gut health cannot be ignored, with the FDA responding by calculating dietary exposure to emulsifiers and assessing their safety anew.
However, this FDA study has its limitations, looking retrospectively only up to 2010.
The quick pace at which the food industry and additive use are growing means regulations will likely never keep up.
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It’s up to you to protect yourself.
If you’re going to buy food with ingredients, at the very least check the label. If something seems like it shouldn’t be in your food, it probably shouldn’t. Better safe than sorry.
Additionally, some of these don’t even make it onto the label at all!
For example, in skim milk, vitamins A and D are added, but they’re fat soluble so they require the addition of emulsifiers, but you won’t find them on the label at all!
If you’re going to buy food with ingredients, at the very least check the label. If something seems like it shouldn’t be in your food, it probably shouldn’t. Better safe than sorry.
Additionally, some of these don’t even make it onto the label at all!
For example, in skim milk, vitamins A and D are added, but they’re fat soluble so they require the addition of emulsifiers, but you won’t find them on the label at all!
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This may not seem like a big deal since they are in small quantities, but if you can avoid them I think it is optimal for your long term health.
Throughout my own experience and working with several others with gut problems, this can be a major cause of unexplained problems.
Be careful out there.
Throughout my own experience and working with several others with gut problems, this can be a major cause of unexplained problems.
Be careful out there.
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