Lets freaking go: ‘This is revolutionary!’: Breakthrough...

Chubby♨️@kimmonismus
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Jun 02, 2025
~2 min read
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Lets freaking go: ‘This is revolutionary!’: Breakthrough cholesterol treatment can cut levels by 69% after one dose
Countless people die from cardiovascular diseases. The biggest problem: heart attacks due to calcified arteries.
Without exaggeration, this could be over forever with a single injection!
Let me explain how it works:
Countless people die from cardiovascular diseases. The biggest problem: heart attacks due to calcified arteries.
Without exaggeration, this could be over forever with a single injection!
Let me explain how it works:
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1. A new gene therapy from Verve Therapeutics is currently causing quite a stir because it could herald a genuine medical revolution: VERVE-102, as the therapy is called, has shown in initial clinical trials that it can reduce LDL cholesterol - the “bad cholesterol” - by over 50 %,
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2. and that with just a single infusion.The special thing about it is the mechanism of action: VERVE-102 intervenes directly in the genetic material of the liver cells and permanently switches off a gene called PCSK9.
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3. This gene plays a key role in regulating cholesterol levels - if it is deactivated, the body can break down LDL cholesterol much more efficiently.
What makes this therapy so significant is above all its potential as a one-off treatment.
What makes this therapy so significant is above all its potential as a one-off treatment.
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4. In contrast to existing medications, which have to be taken daily or regularly and often lead to problems with adherence, VERVE-102 could have a long-term - perhaps even lifelong - effect with a single intervention.
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5. This would be an enormous relief, especially for people with a genetic form of high cholesterol or for those who cannot achieve sufficient control of their levels despite intensive drug treatment.
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6. In addition, the therapy has been well tolerated in the study so far: there have been no serious side effects, which raises hopes that this approach can be widely used in the future.
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7. In a world where cardiovascular disease remains the most common cause of death, a safe, permanent reduction in LDL cholesterol could save lives - without the daily pills, without constant blood tests, without constant anxiety.
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8. The therapy has not yet been approved, but it already shows where the medicine of the future could go: away from pure symptom treatment and towards permanent, targeted solutions at the root of the problem. That is what makes this approach so revolutionary
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10. Thanks for reading!
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