Autoimmune diseases CAN be healed, if you know how to approach them...
Dalton (Analyze & Optimize)@Outdoctrination
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Oct 08, 2025
~3 min read
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Autoimmune diseases CAN be healed, if you know how to approach them properly.
Here are 10 KEY CAUSES of autoimmunity - and what to do about them:
Here are 10 KEY CAUSES of autoimmunity - and what to do about them:
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1. LEAKY GUT.
Intestinal permeability leads to inflammation systemically, skewing T cells away from anti-inflammatory to pro-inflammatory types.
Roughly 80% of your immune system is in the gut, and if it's off it is perhaps the primary trigger of autoimmunity.
Intestinal permeability leads to inflammation systemically, skewing T cells away from anti-inflammatory to pro-inflammatory types.
Roughly 80% of your immune system is in the gut, and if it's off it is perhaps the primary trigger of autoimmunity.
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2. DYSBIOSIS.
Again we see how vital the gut is.
Butyrate producing bacteria are vital to keep these T cells in check (more anti-inflammatory Tregs),
while low butyrate production impairs the immune response.
Butyrate has multiple direct anti-inflammatory effects on other tissues as well.
Again we see how vital the gut is.
Butyrate producing bacteria are vital to keep these T cells in check (more anti-inflammatory Tregs),
while low butyrate production impairs the immune response.
Butyrate has multiple direct anti-inflammatory effects on other tissues as well.
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3. LOWERING STRESS.
Seemingly paradoxically, while glucocorticoids are given to treat these conditions, in the long run cortisol can actually enhance the inflammatory response in response to tissue damage.
These tissues can become damaged due to excessive adrenaline, and leaks pro-inflammatory damage associated molecular patterns which drive inflammation.
Seemingly paradoxically, while glucocorticoids are given to treat these conditions, in the long run cortisol can actually enhance the inflammatory response in response to tissue damage.
These tissues can become damaged due to excessive adrenaline, and leaks pro-inflammatory damage associated molecular patterns which drive inflammation.
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4. MASTERING ESTROGEN.
Autoimmune conditions are much more common in woman than in men, and estrogen seems to be a culprit.
Estrogen in excess can have pro-inflammatory effects on the immune system, especially in conditions like lupus.
This is not true for all autoimmune conditions - in some cases it can have a protective effect (MS) but the bottom line is it needs to be kept in check.
Autoimmune conditions are much more common in woman than in men, and estrogen seems to be a culprit.
Estrogen in excess can have pro-inflammatory effects on the immune system, especially in conditions like lupus.
This is not true for all autoimmune conditions - in some cases it can have a protective effect (MS) but the bottom line is it needs to be kept in check.
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5. MITOCHONDRIAL FUNCTION
If your mitochondria aren't working properly:
◇ Immune cells reprogram to become more inflammatory
◇ They generate more inflammatory components
◇ They cannot generate enough energy to resolve inflammation
The inflammatory state is one of mitochondrial dysfunction.
If your mitochondria aren't working properly:
◇ Immune cells reprogram to become more inflammatory
◇ They generate more inflammatory components
◇ They cannot generate enough energy to resolve inflammation
The inflammatory state is one of mitochondrial dysfunction.
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6. VAGUS NERVE OPTIMIZATION
The vagus nerve is our primary parasympathetic (calming) nerve.
It connects to various tissues that harbor immune cells, and signals to them to calm down and promote anti-inflammatory effects.
This is critical in autoimmunity.
The vagus nerve is our primary parasympathetic (calming) nerve.
It connects to various tissues that harbor immune cells, and signals to them to calm down and promote anti-inflammatory effects.
This is critical in autoimmunity.
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7. DIFFERENTIATING NUTRIENTS
The immune system has cells that divide and differentiate rapidly.
These processes require lots of:
◇ Zinc
◇ Vitamin A
◇ Vitamin D
◇ Vitamin C
in order to work properly.
Without them, immune cells can't become their proper form and can get stuck in the inflammatory state.
The immune system has cells that divide and differentiate rapidly.
These processes require lots of:
◇ Zinc
◇ Vitamin A
◇ Vitamin D
◇ Vitamin C
in order to work properly.
Without them, immune cells can't become their proper form and can get stuck in the inflammatory state.
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8. OMEGA 3 / 6 BALANCE
Omega 3 fats (grass fed beef, pastured eggs, seafood) metabolize into mediators known as resolvins - which help to halt the inflammatory processes.
Omega 6s (pork, chicken, seed oils) do the opposite, metabolizing into pro-inflammatory mediators.
They compete with each other and thus the ratio between them is a key determinant of the inflammatory response.
Omega 3 fats (grass fed beef, pastured eggs, seafood) metabolize into mediators known as resolvins - which help to halt the inflammatory processes.
Omega 6s (pork, chicken, seed oils) do the opposite, metabolizing into pro-inflammatory mediators.
They compete with each other and thus the ratio between them is a key determinant of the inflammatory response.
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9. LYMPH OPTIMIZATION
Your lymphatic system is not only imperative for clearing out cellular debris that can trigger the inflammatory processes,
but it also ensures that lymph fluid and immune cells are moving to lymph nodes where they can properly mature.
No flow = more inflammation.
Your lymphatic system is not only imperative for clearing out cellular debris that can trigger the inflammatory processes,
but it also ensures that lymph fluid and immune cells are moving to lymph nodes where they can properly mature.
No flow = more inflammation.
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10. OXIDATIVE STRESS
The production of reactive oxygen species is perhaps the most fundamental trigger of inflammation.
Within cells, these molecules (ROS) trigger the activation of the master inflammatory regulator NF-κB,
which is responsible for every single inflammatory process in autoimmunity.
The production of reactive oxygen species is perhaps the most fundamental trigger of inflammation.
Within cells, these molecules (ROS) trigger the activation of the master inflammatory regulator NF-κB,
which is responsible for every single inflammatory process in autoimmunity.
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Autoimmunity sucks, but it is treatable and fixable with the right approach.
If you want to get some personalized / targeted help from us with this or any other health goal, schedule a free call here: go.prism.miami/consultation
If you want to get some personalized / targeted help from us with this or any other health goal, schedule a free call here: go.prism.miami/consultation