Collagen can reverse aging in the brain, even in small amounts,...
Dalton (Analyze & Optimize)@Outdoctrination
109 views
Oct 22, 2025
~2 min read
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Collagen can reverse aging in the brain, even in small amounts, according to a recent study.
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This study was published in 2019 in the Journal of Nutrients.
Healthy patients age 49-63 received just 5g of collagen a day, a bit over a teaspoon.
They got imaging on their brains to see the structural impacts collagen would have, along with tests on memory and learning.
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Healthy patients age 49-63 received just 5g of collagen a day, a bit over a teaspoon.
They got imaging on their brains to see the structural impacts collagen would have, along with tests on memory and learning.
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Collagen increased white matter in the brain after just 4 weeks.
White matter is the tissue in brain that mainly reflects the axons of neurons - the part that transmits signals to other neurons.
This indicates much better overall brain health.
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White matter is the tissue in brain that mainly reflects the axons of neurons - the part that transmits signals to other neurons.
This indicates much better overall brain health.
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Collagen also improved cognitive scores.
On the word list memory assessment, which measures short term retaining ability, people taking collagen had a marked improvement.
The same was true for the standard verbal paired associate learning test - which measures learning, attention and memory.
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On the word list memory assessment, which measures short term retaining ability, people taking collagen had a marked improvement.
The same was true for the standard verbal paired associate learning test - which measures learning, attention and memory.
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There were some indications that collagen could improve overall quality of life as well.
While not statistically significant, people taking collagen reported greater quality of life in:
- Mental
- Social
- Physical
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While not statistically significant, people taking collagen reported greater quality of life in:
- Mental
- Social
- Physical
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Collagen's ability to increase white matter in the brain (FA-BHQ) was also directly related to the improvements on the cognitive assessments (S-PA)
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Why does collagen help the brain?
When consuming collagen, some of its peptides remain intact:
➠ Prolyl-hydroxyproline (Pro-Hyp)
➠ Hydroxyprolyl-glycine (Hyp-Gly)
➠ Glutamyl-hydroxyprolyl-glycine (Glu-Hyp-Gly)
They each have unique biological effects - like:
◇ Stimulating angiogenesis (blood vessel formation)
◇ Increasing BDNF (brain cell growth + proliferation)
◇ Reducing microglia activation (neuroinflammation)
It's unique in this aspect from the vast majority of other protein sources.
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When consuming collagen, some of its peptides remain intact:
➠ Prolyl-hydroxyproline (Pro-Hyp)
➠ Hydroxyprolyl-glycine (Hyp-Gly)
➠ Glutamyl-hydroxyprolyl-glycine (Glu-Hyp-Gly)
They each have unique biological effects - like:
◇ Stimulating angiogenesis (blood vessel formation)
◇ Increasing BDNF (brain cell growth + proliferation)
◇ Reducing microglia activation (neuroinflammation)
It's unique in this aspect from the vast majority of other protein sources.
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I've written more about the unique benefits of collagen and how it works below.
x.com/Outdoctrinatio…
x.com/Outdoctrinatio…
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