Glutathione is often called the master antioxidant, but it’s...

Glutathione is often called the master antioxidant, but it’s actually regulated by melatonin (PMID: 20868358)

Besides sleep, melatonin also regulates inflammation, immunity, antioxidant activity, and autophagy the process of cell recycling

youtu.be/AireY34ggw8

Melatonin co-ordinates vital rejuvenation processes in your sleep:
- the largest surge in growth hormone during the 24h cycle
- increased mitochondrial SOD (powerful antioxidant)
- NAD recycling through sirtuins
- autophagy and clearance of cell debris
- DNA repair

"Melatonin has been effectively used to combat oxidative stress, inflammation, and cellular apoptosis and to restore tissue function in a number of human trials; its efficacy supports its more extensive use in a wider variety of human studies." (PMID: 27500468)

Melatonin and vitamin D have very similar hormonal effects and they act like counter opposite light or darkness sensors (PMID: 36235587)

But melatonin levels drop with age, which is one of the reasons for the decline in sleep quality and duration seen in aging (PMID: 10852441)

This has obvious implications for health and longevity