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Is SV40 Large Tumor Antigen required for SV40 origin of replication activity. No
Here we detect Pfizer plasmid DNA in a colon tumor biopsy 1 year after vaccination. And its not small amounts of DNA. Its so much DNA that it can only be explained by plasmid amplification post vaccination or genome integration and amplification.
Variants are found in the SV40 Promoter that do not exist when you sequence the vaccine directly suggestive of replication errors once transfected into mammalian cells.
I will be presenting on this at the Back to Basics conference this week in Waltham Mass. <a target="_blank" href="https://www.backtobasicsconference.com" color="blue">backtobasicsconference.com</a>
More on this link. <a target="_blank" href="https://open.substack.com/pub/anandamide/p/sv40-origin-of-replication-in-mammalian?r=jhcie&utm_campaign=post&utm_medium=web" color="blue">open.substack.com/pub/anandamide…</a>
Keep in mind there are many peer reviewed studies that show vaccine persistence tapering over 30-60 days in various tissues. This sample being 1 year out is an outlier but we looked in tissues that were likely to be enriched for detection (Spike IHC positive tumor samples). While the fact chokers criticize this, remind them there is no justifiable reason for SV40 sequences to be in their vaccine. These are all risk and no gain. Moderna has none and is evidence that they are superfluous. You should not have mammalian origins of replication in your vaccine. You only do that if you got your plasmid from your Gene Therapy division... Which Pfizer is on record actually doing.
@Carborundu55651 As for P53, not only will SV40 promoters bind to it, but spike protein will lower its expression.