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10 potent tools to 10x your dopamine levels THREAD 🧵
DISCLAIMER: This is not medical advice. I am not a doctor. Consult a doctor before using any supplement or drug. Do your own research on the risks of each supplement or drug prior to using.
Dopamine is the #1 key to success It's essential for: - motivation/willpower - attention/focus Strategically enhancing dopamine while simultaneously using it in a productive manner sets you up to win big With that, let's dive right into it...
1) SAFFRON FIrst up is Saffron Everyone knows about Saffron as a culinary spice But few understand it's cognitive-enhancing power Here's how it works:
Saffron contains dopaminergic bioactives such as crocin that: - Inhibit Dopamine Reuptake - Inhibit Noradrenaline Reuptake - Block Serotonin 5-HT2C Receptors And according to a human study out of Iran, Saffron is as effective as Ritalin for treating ADHD Let that sink in...
From my experience, extracts rich in crocin such as the ones below are much more stimulating I've been taking 60mg daily as of late and haven't looked back <a target="_blank" href="https://lddy.no/1eqcp" color="blue">lddy.no/1eqcp</a>
2) CATUABA BARK When I tried Catuaba for the first time two years ago, I blown away by how potent it was It was noticeably stimulating without the typical stimulant jitters And when you look at the science behind it, it makes total sense
Catuaba: - Increases dopamine release - Inhibits dopamine reuptake - Prevents dopamine breakdown (mild) While Trichilia catigua is considered “true Catuaba..." Erythroxylum catuaba is very similar and is just as potent in my experience If not more potent...
3) BROMANTANE Bromantane is my favorite compound on this entire list Here's why: Bromantane boosts dopamine levels... But unlike something like Adderall, it does so without addiction, tolerance, or withdrawal Read that again...
How? 1) Increases DA synthesis (TH/AAAD) 2) Increases DA sensitivity (BDNF/GDNF) It has a noticeable acute effect that a) builds with consistent use b) synergizes with other dopaminergics While it's safe overall IMO, it’s not a supplement nor is it an approved drug in the USA
4) CORDYCEPS Cordyceps is infamously known as “Himalayan Viagra” It reliably increases testosterone via bioactives that are analogous in structure to luteinizing hormone Testosterone indirectly boosts dopamine via epigenetic mechanisms, but Cordyceps doesn't stop there...
Cordyceps is not only "Himalayan Viagra" It's also "Herbal Bromantane" It shares 2 key benefits with Bromantane: 1) Boosts dopamine synthesis by upregulating tyrosine hydroxylase 2) Enhances endurance & oxygen utilization To be honest, Bromantane is much more potent tho
5) RHODIOLA ROSEA Cordyceps isn’t the only dopamine-boosting adaptogen As it turns out, Rhodiola Rosea also powerfully boosts dopamine, in more way than one - Blocks DA breakdown (COMTi/MAOi) - Enhances dopaminergic neurogenesis - Increases BBB permeability to dopamine
This may surprise some of you who consider it a calming, anti-stress herb But extracts that are rich in SALIDROSIDE (rather than rosavin) are much more stimulating in my experience I've been using this for 8 months and it's been a game-changer <a target="_blank" href="https://www.amazon.com/dp/B0751HBW2F?maas=maas_adg_25A1C1742F6559E782730E5FF028AE27_afap_abs&ref_=aa_maas&tag=maas" color="blue">amazon.com/dp/B0751HBW2F?…</a>
6) ISTRADEFYLLINE Like Bromantane, this one is technically a pharmaceutical drug It's used in Parkinson's Disease where dopamine levels are low due to neurodegeneration It indirectly increases dopamine (D2 receptor) signaling via blocking the adenosine A2A receptor
Because A2A receptors form heteromeric complexes with dopamine D2 receptors.... Blocking A2A increases D2 signaling This improves certain Parkinson's symptoms & may help depression And unlike caffeine, it shouldn't induce cardiovascular side effects or dependence
7) VIGNATEX Vignatex is an innovative combination of a) mung bean b) passionflower These 2, especially mung bean, contain compounds that slow the breakdown of dopamine (via MAO inhibition)
While Passionflower also inhibits MAO, it mainly works to smooth out any potential jitters via enhancing GABAergic activity To be honest, I personally wouldn't use Vignatex for nootropic purposes But it may potentially be useful for lowering prolactin or Restless Leg Syndrome
8 + 9) SABROXY & POLYGALA Sabroxy & Polygala are 2 of the heavy hitters on this list And Notable Focus contains both Sabroxy boosts dopamine via its key bioactive Oroxylin A, a potent dopamine reuptake inhibitor Polygala works similarly via yuanzhi-1 & also inhibits MAO
Because I formulated Notable, I'm biased... But I strongly believe this is one of the most potent dopamine-boosting supplements on the market I recommend 2-4 capsules, or 1 capsule dumped & held under tongue Very synergistic w/ caffeine <a target="_blank" href="http://meetnotable.com" color="blue">meetnotable.com</a>