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Euan Arnott
@Nucleocapsoid
Just simplifying Andean hantavirus epidemiology for my own clarity...

Cluster of 7 people were infected on cruise ship by initial zoonotic passenger (onset 6th April) with Serial Interval
SI = 22 +/- 4 days

French lady was SI = 34 d
*or* onward transmission from 1st cluster
Euan Arnott
@Nucleocapsoid
If *onward* transmission from 1st cluster of 7 cases were to follow similar timing, we wouldn't EXPECT peak of any 2nd cluster until ~May 15th, with likely window extending out to ~May 27th.

Unfortunate French lady in ICU extends *monitoring* timeline still further to mid-June.
Euan Arnott
@Nucleocapsoid
So coming 2 weeks will reveal whether there was significant onward transmission from 1st cluster of 7 patients.

This will alarm / re-assure about behaviour of this particular Clade-3 virus.

But actual elimination of onward transmission will require further patience until JUNE.
Euan Arnott
@Nucleocapsoid
Above, I have ignored US passenger with weak +ve (& now -ve follow-up) PCR, but timing of French lady's potential contagiousness at *point of evacuation* (🚨) has same effect on timeline as US person being truly positive.
Euan Arnott
@Nucleocapsoid
Sick person on Tristan da Cunha doesn't affect timeline either, but does extend number of people exposed.
Euan Arnott
@Nucleocapsoid
Which reminds us there are further *potential* COMMUNITY chains of transmission from Cluster-1 to watch out for in:

1) St Helena & Ascension
2) JOHANNESBURG, S Africa
3) GENEVA, Switzerland

Two big, connected METROPOLISES there...

Good luck all.
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