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NootBro
@nootropicguy
How to Repair Your Gut

THREAD
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NootBro
@nootropicguy
Disclaimer: This is NOT medical advice. I am NOT a doctor. Always consult with a qualified physician before starting any health regimen or taking any dietary supplement, herb, or drug. Research all supplements, herbs, or other interventions before using.
NootBro
@nootropicguy
It's impossible to be in optimal health without a healthy gut

Gut issues can cause or contribute to:

- chronic fatigue
- autoimmune disease
- hormonal dysregulation
- psychiatric/neurological disorders
- cardiovascular disease
- & many more
NootBro
@nootropicguy
This thread will touch on:

- possible root causes
- diagnostic testing
- elimination diet
- anti-microbial regimen
- microbiome revitalization

Note that the optimal treatment will vary for each individual depending on their diagnostic testing results & health profile
NootBro
@nootropicguy
0) BACKGROUND ON GUT ISSUES

Most "gut issues" are some combo of:

- SIBO
- Candida
- Parasites
- Intestinal permeability ("leaky gut")
- Insufficient digestive horsepower

There is significant interplay between these and usually more than 1 is present
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NootBro
@nootropicguy
1) DIAGNOSTIC TESTING

Sometimes it's possible to identify the issue via symptoms though this isn't always accurate

If you can narrow it down, consider getting one of the cheaper condition-specific tests to confirm

White tongue = candida
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NootBro
@nootropicguy
If you have no idea, the Genova Diagnostics GI Effects Comprehensive profile is the gold standard for overall gut health

Less expensive tests include (but are not limited to):

SIBO:
- Hydrogen/methane breath tests

CANDIDA:
- Candida Antibodies (IgG, IgA, IgM)
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NootBro
@nootropicguy
PARASITES:
- Genova Parasite Add-On

LEAKY GUT:
- Lactuose/mannitol (urine)
- Antigenic permeability screen

LOW STOMACH ACID:
- Heidelberg test
- Chloride blood test
NootBro
@nootropicguy
2) TEMPORARY ELIMINATION DIET

REMOVE:
- Soy, corn, grains/oats, gluten/gliadin
- Dairy
- Added sugars & artificial sweeteners
- Artificial & "natural" flavors
- Legumes, nuts, & seeds
- Seed/vegetable oils
- Alcohol
- Tap water

REDUCE:
- Coffee
- Nicotine
- Blue light
NootBro
@nootropicguy
Other key points:

- Avoid non-organic foods (esp GMO)
- Opt for low FODMAP fruits & veg
- Severe cases may require carnivore
- Increase sun & red light exposure

Keep a log of all food intake and corresponding symptoms and remove additional foods/ingredients as needed
NootBro
@nootropicguy
3) DIGESTIVE HORSEPOWER

Some gut issues can actually be caused by low stomach acid or digestive enzyme insufficiency, which means:

- suboptimal food breakdown
- poor nutrient absorption
- pathogen overgrowth
NootBro
@nootropicguy
This is especially relevant if you've ever had reflux issues

Solution: Betaine HCL & Digestive Enzymes

The following may also be helpful:

- Thorne BioGest
- Digestive Bitters
- Pepsin

Use carefully and research prior to use

Take before eating
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NootBro
@nootropicguy
4) FIX LEAKY GUT

The elimination diet will reduce inflammatory triggers and allow our intestinal lining to heal

To expedite this process, we can add

- 5-10g L-Glutamine (1-2 weeks max) or Kettle & Fire bone broth daily

Use caution when using L-Glutamine (ammonia production)
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NootBro
@nootropicguy
- 1.2 to 2.4g Butyric Acid as Sodium Butyrate

- 3.0g Goat milk colostrum

Note that goat milk is generally much easier to digest than cow's milk

If you react poorly to colostrum, remove it or try taking it with digestive enzymes
NootBro
@nootropicguy
The following herbs are also helpful for leaky gut:

- Slippery elm bark
- Marshmallow root
- Deglycyrrhizinated licorice root
- Aloe vera (preferably in juice form)

There's a product called DGL Plus with all of these

Organic Throat Coat tea also contains most of these
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NootBro
@nootropicguy
Highly recommended adhering to the elimination diet & leaky gut protocol for 2+ weeks before starting any anti-microbial protocol

Also recommend working with a skilled practioner for these next steps, which aren't always necessary

Diet + leaky gut repair often does the trick
NootBro
@nootropicguy
4) ANTI-MICROBIAL REGIMEN

This regimen will vary by situation

Make sure your selections are geared toward the right pathogens

Recommend 3+ anti-microbials

Binders like bentonite clay or zeolite may also helpful depending on your situation


NootBro
@nootropicguy
Additional Notes:

In extreme scenarios, ivermectin & LL-37 may help but work with a doctor

Check for interactions b/t each agent and existing agents/conditions

The pathogen "die-off" may cause flu-like symptoms

Be strategic in your selections based on pathogen type
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NootBro
@nootropicguy
5) REPOPULATE MICROBIOME

Generally, the anti-microbial protocol is ~4 weeks with occassional "off days" but this can vary

You'll need to repopulate the microbiome during and after your anti-microbial regimen

That said, I'd be cautious with probiotic agents if SIBO is present
NootBro
@nootropicguy
You can start probiotics during anti-microbial regimen

Choose at least 2:

- Seed Probiotic
- Visbiome VSL #3
- Goat Kefir (minimal lactose if any)
- Caprobiotics
- Thorne Floramend

For candida, Saccharomyces boulardii is especially helpful

My favs: Seed, Visbiome, & Kefir
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